BROMOCRIPTINE ADDED TO COMBINED LETROZOLE-METFORMIN VERSUS BILATERAL OVARIAN DRILLING IN CLOMIPHENE-RESISTANT INFERTILE WOMEN WITH POLYCYSTIC OVARY SYNDROME
Asmaa Abd El-Shakour Mosad, Ahmed Yousif Rezk, Mohamed A. Hady Farg and Ahmed Samy Saad
Department of Obstetrics and Gynecology, Faculty of Medicine, Benha University
Back ground and Aim Of The Work: To compare the effectiveness of laparoscopic ovarian drilling versus bromocriptine added to combined letrozole and metformin in clomiphene citrate-resistant infertile women with polycystic ovary syndrome.
Patients And Methods: a prospective, randomized study included 112 primary infertile women with PCOS divided into two groups: Group 1 underwent laparoscopic ovarian drilling, Group 2 received bromocriptine, letrozole and metformin, ovulation rate and pregnancy rate were compared between both groups. Results: ovulation and pregnancy rate was noted to be higher in a medical treatment group than LOD group but not statistically significant, P- Value =0.28
Conclusion: LOD as an option in the management of infertile women with PCOS especially as a second line treatment after failure of medical induction of ovulation to eliminate the risk of surgery and anaesthesia.