HYMENOLEPIS NANA COINFECTION WITH HELICOBACTER PYLORI IN INSTITUTIONALIZED EGYPTIAN CHILDREN AND ADOLESCENTS AND THEIR IMPACT ON SOME NUTRITIONAL PARAMETERS
Mahmoud A. Mohammad* Laila A. Hussein* and Mai A. Hegazi
Department of Nutrition, National Research Center* and Department of Parasitology, Faculty of Medicine for Girls, Al Azhar University, Egypt
The study assessed the prevalence of Hymenolepis nana and Helicobacter pylori among 100 Egyptian children and adolescents of both sexes (6-16 years old) residing two welfare institutes in Giza and Cairo. The overall prevalence of H. nana was 25% and H. pylori was 82% while single H. nana was 6%, single H. pylori was 52% and coinfection of H. nana and H. pylori was 19%. A total of 88 subjects were selected and divided into four groups: Group 1 (12 free controls), Group 2 (6 H. nana single infection), Group 3 (52 single H. pylori infection) and Group 4 (19 H. nana and H. pylori coinfection). All groups were subjected to the following nutritional parameters: anthropometric measures, haematological study (Hb %, RBCs count, WBC count and haematocrit % value) and biochemical estimation of vitamin B12 and folate levels in plasma. The study showed that the Z score of height for age (HAZ) below-2 representing stunting and the Z score for weight for age (WAZ) below-2 representing wasting were significantly higher among group 4, followed by group 3 while group 2 showed insignificant increase respectively versus control. Body mass index by Z score showed non-significant difference among all the studied groups versus control. Group 4 had the highest significant decrease in mean Hb %, RBCs count and haematocrit % values followed by slight significant decrease in group 3 and 2 versus control denoting iron deficiency anaemia. WBC mean count showed a high significant increase in group 4 followed by moderate leucocytosis in group 3 and group 2 versus control. The mean plasma levels of vitamin B12 and folate were significantly lower in group 4 followed by group 3 and finally group 2 versus control. In conclusion the study showed extremely high prevalence of H. nana and H. pylori among Egyptian welfare residents and that their coinfection has a synergetic negative adverse effect on their nutritional status.