BLOOD TRANSFUSION AS A RISK FACTOR OF NOSOCOMIAL TOXOPLASMOSIS
Nashaat Nassef, Nadia El-Nahas, Samar El-Refai
Parasitology Department, Faculty of Medicine, Menoufiya University
Screening blood for toxoplasmosis is not practiced, so there is a great possibility for its transmission from healthy and volunteer blood donors.This study was performed on 40 hospitalized patients; they were classified into two groups, GI (25 patients who received blood after admission) and GII (15 patients not receiving blood).Anti-Toxoplasma IgM & IgG antibodies were performed for GI before blood transfusion, 11 cases were +ve (3 +ve IgM & 8 +ve IgG). The remaining 14 were still –ve after 2 weeks of blood transfusion; did not show rising titre, but after 4 weeks one case turned +ve. In GII, IgG & IgM antibodies were +ve in 7 cases (2 IgM + 5 IgG), 2 weeks after admission the –ve 8 showed no rising titre, also after 4 weeks no rising titre. PCR in GI showed 3 +ve cases, at admission time after blood transfusion; two cases from the –ve 22 cases turned +ve, so nosocomial Toxoplasma acquired infection is expected.In GII at admission one case was +ve PCR, after 2 weeks the –ve 14 case gave no positivity, so no acquired Toxoplasma infection.