COINCIDENCE OF TOXOPLASMOSIS AND HEPATITIS C VIRUS (HCV) IN FEMALES IN CHILDBEARING PERIOD IN QALUBIA GOVERNORATE
MOHAMED S. YOUNIS, ALI E.ALI, AMINA I.ABDEL-MABOUD, KHALID GHAITH AND AHLAM F.EL-SADEK
Department of Medical Parasitology, Benha Faculty of Medicine, Egypt
This work was to study the coincidence of Hepatitis C virus infection and toxoplasmosis and the implication of that in females in childbearing period in Qalubia Governorate.Hepatitis C virus one step rapid test for HCV antibodies was performed on 103 women. Toxoplasmosis was diagnosed using ELISA IgG and IgM antibodies detection, trying to study whether there is an association between toxoplasmosis and HCV in child bearing women. Results revealed that HCV antibodies were detected in 17(16.9%), IgG in 55(53.4%) and IgM in 10(9.7%) of cases. Toxoplasma seropositivity was 11(64.7%) for IgG in HCV positive cases and 44(51.2%) in negative HCV cases, and was 2(11.8%) IgM in HCV positive cases and 8(9.3%) in negative cases. The highest IgG positivity was 34(61.8%) and 5(50%) in IgM in age group between (31-38y). The seropositivity of IgG was 55.4% in multigravida and 45%in primigravida, 61.1% in rural areas and 35.5% in urban areas. The seropositivity of anti-Toxoplasma IgM was 7.1% in multigravida and 21.1% in primigravida, 9.9%% in rural areas and 9.4% in urban areas. It was concluded that the positivity of anti-Toxoplasma IgG antibodies among HCV positive cases was doubled than that among HCV negative cases, there was an increase of positivity of anti-Toxoplasma IgG antibodies with aging, multigravida and cases living in rural areas. It was recommended that more studies are needed to elucidate the relation between toxoplasmosis and HCV infection.