THE PRENATAL EFFECTS OF MOBILE MICROWAVE RADIATION ON MICE
Khaled Naim Hamdi
Anatomy Department, Faculty of Medicine, Ain Shams University, Cairo, ARE. Present Address: Riyadh College of Health Sciences, King Saud University, KSA
Microwave radiations (MW R) are widespread in human life. The biological hazards of MWR on human and experimental animals especially the prenatal effects of MWR are still unclear and the data are insufficient. The aim of the present study was to investigate the histopathological and ultrastructural prenatal effects of mobile phone microwave radiation on the mice liver. The pregnant mice were divided into three groups, 10 animals each: group one (G1) was the control group with mice unexposed to mobile phone. Group two (G2) mice were exposed for half hour every day during the gestational period with the cell phone in answering state. Group three (G3) mice were exposed for one hour every day during the gestational period with the cell phone in answering state; and 12 hours while the cell phone was in standby state .The microwave radiation was produced by mobile phones operate with microwave frequencies range 900-1800 MHz. Mice fetuses were examined and then were sacrificed with overdose of ether. Liver biopsies were prepared for histopathological and ultrastructural examinations. The mean body weight & length of fetuses of G3 showed statistically significant decrease as compared with G1 (p< 0.05). Congestion of the central vein and dilation of hepatic blood sinusoids were the most frequent histopathological findings. The ultrastructural results were apparent in G3 in the form of dilated RER , loss of mitochondrial cristea and pleomorphic mitochondria, mitochondrial swelling & fragmentation, hepatocytic vaculations, nuclear inclusions and inflammatory cells infiltration in the periportal areas mainly lymphocytes. The results of the present study showed significant reduction of the average body weight and length of fetuses of G2 & G3.The ultrastructural damage that observed in the examined specimens reveal the hepatocellular injuries and consequently systemic impairment of the body functions.