COMPARATIVE STUDY BETWEEN LIDOCAINE 2% AND DEXAMETHASONE LOCAL WOUND INFILTRATION EFFECT ON POSTOPERATIVE PAIN AFTER CESAREAN SECTION
Yossra S Lasheen
Obstetrics and Gynecology Department - Faculty of Medicine - Cairo University
Objective: to compare the efficacy and safety of Lidocaine 2% versus Dexamethasone injected locally in cesarean section wound as pain relieving agents. Materials & methods: A randomized single-blinded study in which 120 primigravidas candidate for CS were included. Participants were equally randomized into two groups; group A in which patients received 10ml Lidocaine 2% and group B in which patients received 16 mL Dexamethasone. In both groups, the drugs were given via local infiltration in the subcutaneous layer of the CS wound immediately after skin closure. Pain control was assessed post-operatively in the first 24 hours using the visual analogue scale (VAS) in addition the need for additional analgesia was recorded. Results: There was a statistically significant lower VAS score in group A when compared to those in group B (0.67 ± 1.41 vs. 3.47±2.38, 0 vs. 5.2±2.74, 0.67 ±1.41 vs.4.4±2.96, 0.73±1.4 vs. 4.4±3.62 and 2.4±3.7 vs. 5.47 ±4.07 at 1,4,6,12 and 24 hours postoperative respectively, P value <0.001). There was also a higher percentage of women who needed additional post-operative analgesia among Dexamethasone group (80 % vs 20%, P value < 0.001). Conclusion: Local injection of Lidocaine 2%, in CS wounds, has an upper hand in reducing the post-operative pain and showed a lesser need for post-operative analgesia when compared to local Dexamethasone injection.