IMMUNOLOGICAL AND HISTOPATHOLOGICAL STUDIES ON TOXOCARAL GRANULOMAS
Khaled Abd El-Aziz Mohammad*, Alaa Abd El-Aziz Mohammad Samn** and Mohammad K. Yassin**
*Parasitology Department, Faculty of Medicine (Damietta), **Zoology Department, Faculty of Science (Cairo), Al-Azhar University
One hundred and three laboratory bred albino mice were used to carry out this study. Three mice of these were used for testing the infectivity of Toxocara eggs and the remainder 100 mice were classified into 75 infected mice and 25 control non-infected mice. The infected groups were given 500 infective eggs. Mice were sacrificed at 3 weeks interval up to 10 weeks. Immunohistochemical study which is a combination of immunological and pathological changes was performed to determine the differential population of inflammatory cells in the reaction produced to Toxocara canis infection.