ASSESSMENT OF OVARIAN VOLUME AND VASCULARITY BY THREE-DIMENSIONAL ULTRASONOGRAPHY IN CASES OF POLYCYSTIC OVARY SYNDROME
Samah Aboul Gheit
Department of Obstetrics and Gynecology, Cairo University
Objective: The aim of this study was to compare 3D power Doppler characteristics of intra-ovarian vascularity in women with polycystic ovary syndrome (PCOS) and normal controls.
Methods: The study included 2 groups; a study group (n = 30) with PCOS and a control group (n = 30) of normal eumenorrheic women. All women were evaluated with measuring FSH, LH, LH/FSH ratio, testosterone and progesterone. 3D power Doppler transvaginal ultrasonography was done on day 8 of menstrual cycle to determine Doppler flow indices of intraovarian blood flow. In addition, ovarian volume, follicle number and volume, stromal volume and stromal echogenicity were determined.
Results: In PCOS cases, Vascularization index (VI) was 4.15 ± 1.98, Flow index (FI) was 49.37±4.01 and Vascularization flow index (VFI) was 2.09±0.99 versus 1.56±1.17, 43.25±4.68 and 0.77±0.85, respectively, in control group with a p < 0.001 for all comparisons. Ovarian volume was significantly larger in PCOS (p < 0.001). Stromal volume was not significantly different in the 2 groups (p = 0.153). Stromal echogenicity was increased in 53% of PCOS and none of controls. Total ovarian VI, FI and VFI were negatively correlated with BMI, but not correlated with age or AFC in PCOS cases.
Conclusion: PCOS women have a larger ovarian volume and greater stromal blood flow compared to normal ovulatory women. Doppler flow indices were correlated with BMI but not with LH.