COMPARISON BETWEEN ALPHA GST AND SERUM AMINOTRANSFERASES IN SCHISTOSOMIASIS MANSONI WITH OR WITHOUT HCV AND HBV
Maymouna El-Sayed Bakr*, Soraya Abdel-Aziz Sharaf, Abel-Gawad El-Sayed Saad, Elamir Mahmoud Amir and Ayman Aly Ahmed
Parasitology Departments, *Faculty of Medicine and National Liver Institute Menoufiya University
The present study was done to evaluate α-Glutathione-S-transferase as a new biochemical marker for hepatocellular damage in schistosomiasis mansoni patients, with or without chronic hepatitis C and chronic hepatitis B. Alpha GST, ALT and AST were assayed in sera of 55 schistosomiasis patients: 20 with HCV (Group I), 19 with HBV (Group II) and 16 pure S. mansoni (Group III) in addition to 20control healthy subjects (Group IV). The study revealed that measurement of α-Glutathione- S-Transferase in serum was less sensitive and less specific but more accurate than ALT and AST as a marker of liver affection in those patients.